Laurent MacKay

email firstname.lastname@gmail.com

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Education
PhD Physiology, McGill University
MSc Physics, McGill University
Bsc Biophysics, Concordia University

As a mathematical physiologist, I am interested how the dynamics of biology produce robust physiological states and how perturbations to these dynamics result in diseased states. I use differential equations (ODEs, PDEs, SDEs) in combination with dynamical systems approaches (e.g., bifurcation analysis and multiple-timescale analysis) to build and analyze mathematical models of biological phenomenon, yielding mechanistic insight and therapeutic perspectives.

Previously, I completed my PhD in Physiology from McGill University, where I was advised by Anmar Khadra and primarily worked on problems related to cellular motility with a focus on focal adhesions and the biochemical signaling involved in their regulation.

I am also keenly interested in programming and software design. I love spending time thinking about how to best design my code so that it is both computationally efficient and pleasant to work with.

selected publications

  1. MacKay2021.png
    Deciphering the dynamics of lamellipodium in a fish keratocytes model
    Laurent MacKay, Etienne Lehman, and Anmar Khadra
    Journal of Theoretical Biology, Mar 2021
  2. MacKay2019.png
    Dynamics of Mechanosensitive Nascent Adhesion Formation
    Laurent MacKay and Anmar Khadra
    Biophysical Journal, Sep 2019
  3. MacKay2016.png
    Systematic Characterization of Dynamic Parameters of Intracellular Calcium Signals
    Laurent Mackay, Nicholas Mikolajewicz, Svetlana V. Komarova, and 1 more author
    Frontiers in Physiology, Nov 2016